Gabrio Bassotti Selected Research

Pseudomembranous Enterocolitis (Pseudomembranous Colitis)

12/2018	Clostridium difficile toxin B induces senescence in enteric glial cells: A potential new mechanism of Clostridium difficile pathogenesis.
1/2017	Enteric glial cells counteract Clostridium difficile Toxin B through a NADPH oxidase/ROS/JNK/caspase-3 axis, without involving mitochondrial pathways.
1/2017	Enteric glial cells are susceptible to Clostridium difficile toxin B.
7/2011	Non-IBD colitides: clinically useful histopathological clues.

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Gabrio Bassotti Research Topics

Disease

14	Celiac Disease (Celiac Sprue) 02/2022 - 08/2006
14	Constipation 11/2019 - 01/2004
10	Ulcerative Colitis 01/2022 - 01/2007
9	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 05/2022 - 01/2007
9	Neoplasms (Cancer) 02/2022 - 03/2008
5	Infections 01/2021 - 08/2004
5	Inflammation (Inflammations) 01/2020 - 01/2012
4	Clostridium Infections 01/2021 - 12/2018
4	Hemorrhage 05/2019 - 09/2013
4	Pseudomembranous Enterocolitis (Pseudomembranous Colitis) 12/2018 - 07/2011
4	Colitis 01/2015 - 07/2011
3	Necrosis 01/2021 - 02/2007
3	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 04/2020 - 12/2018
3	Esophageal Achalasia (Megaesophagus) 01/2020 - 01/2005
3	Colorectal Neoplasms (Colorectal Cancer) 01/2020 - 03/2007
3	Opioid-Induced Constipation 03/2019 - 10/2017
3	Diverticular Diseases 03/2019 - 07/2011
3	Diarrhea 12/2018 - 01/2016
3	Crohn Disease (Crohn's Disease) 01/2017 - 01/2007
3	Fistula 01/2015 - 10/2010
3	Adenocarcinoma 12/2012 - 03/2008
3	Ataxia (Dyssynergia) 03/2006 - 01/2004
2	Anemia 04/2022 - 01/2016
2	Intestinal Pseudo-Obstruction (Intestinal Pseudoobstruction) 03/2019 - 01/2019
2	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2019 - 01/2014
2	Peptic Ulcer (Peptic Ulcers) 01/2017 - 10/2015
2	Margins of Excision 12/2015 - 10/2006
2	Liver Diseases (Liver Disease) 09/2015 - 08/2013
2	Enteritis 03/2015 - 02/2014
2	Microscopic Colitis 06/2014 - 07/2011
2	Pathologic Constriction (Stenosis) 11/2013 - 01/2011
2	Barrett Esophagus (Barrett's Esophagus) 01/2013 - 12/2012
1	Iron Deficiencies 04/2022
1	Fatigue 04/2022
1	Avitaminosis (Vitamin Deficiency) 04/2022
1	Diverticulitis 01/2022
1	Cytokine Release Syndrome 01/2021
1	Carcinoma (Carcinomatosis) 01/2020
1	Colonic Neoplasms (Colon Cancer) 01/2020
1	Hematoma 05/2019
1	Rupture 05/2019
1	Splenomegaly 05/2019
1	Ileus 03/2019
1	Ehlers-Danlos Syndrome (Syndrome, Ehlers-Danlos) 01/2019

Drug/Important Bio-Agent (IBA)

10	Pharmaceutical PreparationsIBA 01/2022 - 10/2010
6	Glutens (Glutelin)IBA 04/2020 - 01/2016
6	AntibodiesIBA 06/2017 - 10/2006
5	CytokinesIBA 01/2021 - 01/2014
5	Anti-Bacterial Agents (Antibiotics)IBA 12/2018 - 08/2004
4	trimethylaminocarboxyldihydroboran (TCDB)IBA 01/2021 - 01/2017
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 03/2008
4	Biological ProductsIBA 10/2019 - 02/2013
4	prucaloprideIBA 03/2019 - 06/2009
3	Proton Pump InhibitorsIBA 01/2017 - 08/2013
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 02/2019
2	InterferonsIBA 01/2021 - 01/2016
2	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2019 - 02/2013
2	Immunosuppressive Agents (Immunosuppressants)IBA 10/2019 - 07/2014
2	linaclotideIBA 01/2019 - 08/2018
2	Virulence Factors (Pathogenicity Factors)IBA 12/2018 - 01/2017
2	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 01/2017 - 03/2006
2	VimentinIBA 10/2016 - 10/2006
2	DesminIBA 10/2016 - 10/2006
2	CollagenIBA 10/2016 - 11/2013
2	NeuropeptidesIBA 10/2016 - 01/2012
2	LaxativesIBA 04/2013 - 04/2012
2	AcidsIBA 12/2012 - 05/2005
1	Adalimumab (Humira)FDA Link 05/2022
1	Biosimilar PharmaceuticalsIBA 05/2022
1	GP2017IBA 05/2022
1	IronIBA 04/2022
1	Immune Checkpoint InhibitorsIBA 02/2022
1	Apoptosis Regulatory ProteinsIBA 02/2022
1	CTLA-4 AntigenIBA 02/2022
1	LigandsIBA 02/2022
1	Imatinib Mesylate (Gleevec)FDA Link 01/2022
1	Dasatinib (BMS 354825)FDA Link 01/2022
1	antineoplaston A10 (A 10)IBA 01/2022
1	Interferon-gamma (Interferon, gamma)IBA 01/2021
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020
1	Interleukin-6 (Interleukin 6)IBA 01/2020
1	NF-kappa B (NF-kB)IBA 01/2020
1	Pentamidine (NebuPent)FDA LinkGeneric 01/2020
1	MicroRNAs (MicroRNA)IBA 01/2020
1	Liposomes (Liposome)IBA 01/2020
1	Messenger RNA (mRNA)IBA 01/2020
1	plecanatideIBA 11/2019
1	Guanylyl Cyclase C AgonistsIBA 11/2019
1	Janus KinasesIBA 10/2019
1	Guanylate Cyclase (Guanylyl Cyclase)IBA 01/2019
1	SteroidsIBA 12/2018

Therapy/Procedure

13	Therapeutics 04/2022 - 08/2004
6	Gluten-Free Diet 03/2017 - 08/2006
3	Psychology Biofeedback (Biofeedback) 03/2006 - 01/2004
2	Blood Transfusion (Blood Transfusions) 11/2018 - 01/2017
2	Surgical Instruments (Clip) 11/2018 - 09/2013
2	Length of Stay 11/2018 - 01/2017
2	Colectomy 12/2015 - 03/2007
1	Laparotomy 05/2019
1	Splenectomy 05/2019